Side Effects
What to keep in mind when starting treatment.
It's important to know what side effects are possible with TALZENNA when taken in combination with XTANDI.
TALZENNA may cause serious side effects, including:
Bone marrow problems called Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML). Some people who have cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during or after treatment with TALZENNA. MDS or AML may lead to death. If you develop MDS or AML, your healthcare provider will stop treatment with TALZENNA.
Symptoms of low blood cell counts are common during treatment with TALZENNA, but can be a sign of serious problems, including MDS or AML. Tell your healthcare provider if you have any of the following symptoms during treatment with TALZENNA:
- weakness
- weight loss
- fever
- frequent infections
- blood in urine or stool
- shortness of breath
- feeling very tired
- bruising or bleeding more easily
Your healthcare provider will do blood tests to check your blood cell counts:
- every month during treatment with TALZENNA
- weekly if you have low blood cell counts that last a long time. Your doctor may stop treatment with TALZENNA until your blood cell counts improve.
Common Side Effects of TALZENNA When Taken in Combination With XTANDI
There are some side effects that are more expected than others. Your doctor may modify your treatment dose or have other suggestions that could be helpful. Here are some common side effects to be aware of:
- Low red blood cell counts
- Low white blood cell counts
- Tiredness or weakness
- Low platelet counts
- Low calcium in the blood
- Nausea
- Decreased appetite
- Low sodium in the blood
- Low phosphate in the blood
- Bone injuries
- Low magnesium in the blood
- Dizziness
- Increased bilirubin in the blood
- Low potassium in the blood
- Changes in your sense of taste
TALZENNA may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider if this is a concern for you.
These are not all of the possible side effects of TALZENNA. Call your doctor for medical advice about side effects.
You are encouraged to report side effects of prescription drugs to the FDA. Visit https://www.fda.gov/medwatch or call 1-800-FDA-1088.
Talk to your doctor about the potential side effects of XTANDI.
